IONC101 is designed to prepare the patient’s immune system for battle. By selectively engaging systemic and intratumoral innate immune sensors, this platform creates an environment primed for potent, targeted tumor attack
Through its unique structure–function relationship, IONC101 delivers a personalized set of tumor-specific antigens while conditioning the patient’s immune landscape, ensuring that newly reprogrammed immune cells have both the signals and the support they need to overcome tumor defenses and sustain a durable anti-cancer response.
IONC201 directly targets solid tumors with a novel payload designed to dismantle immune suppression within the tumor microenvironment.
Delivered via our proprietary tumor-targeted nanoparticle system, the platform reprograms local immune activity to sensitize tumors to immune checkpoint inhibitors. By restoring immune visibility and disrupting resistance pathways, IONC201 transforms “cold” tumors into highly inflamed, treatment-responsive sites, unlocking the full potential of combination immunotherapies.
IONC301 is a patient-derived, cell-based immunotherapy built to reboot the immune system from the ground up. This platform technology reprograms systemic immunity, displaces myeloid-derived suppressor cells, boosts production and recruitment of tumor-infiltrating lymphocytes, and conditions the body to respond to immune checkpoint therapy.
Designed for patients with cancers refractory to immune checkpoint inhibition, IONC301 turns resistance into measurable, durable responses, creating a therapeutic reset for the immune system itself.
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